IGF2BP2 (Homo sapiens)
KH,RRM

RBP Information

Pfam ID Interpro ID Gene ID CISBP-RNA ID Sequence source
PF00013 (KH_1)
PF00076 (RRM_1) 		IPR018111
IPR000504 		ENSG00000073792 T22209_0.6 Ensembl (2011-Oct-26) Link out

Directly determined binding motifs

Name/Motif ID Species Sequence Logo IUPAC Type/Study/Study ID RBD
Identity
IGF2BP2
M032_0.6		 Homo sapiens VMAHWCA RNAcompete
Ray et al.(2013)
RNCMPT00033 		(Direct)
IGF2BP2
M294_0.6		 Homo sapiens Sequence logo not available CAU PAR-clip
Cook et al.(2011)
356_20371350 		(Direct)

Motifs from related RBPs

Name/Motif ID Species Sequence Logo IUPAC Type/Study/Study ID RBD
Identity
IGF2BP1
M296_0.6 		Homo sapiens AAGCACCCGUU SELEX
Cook et al.(2011)
359_12507992 		0.749
IGF2BP1
M293_0.6 		Homo sapiens Sequence logo not available CAU PAR-clip
Cook et al.(2011)
355_20371350 		0.749
IGF2BP3
M295_0.6 		Homo sapiens Sequence logo not available CAUU PAR-clip
Cook et al.(2011)
357_20371350 		0.741
IGF2BP3
M163_0.6 		Homo sapiens AMAHWCA RNAcompete
Ray et al.(2013)
RNCMPT00172 		0.741
For this family, RBPs with RBD identity > 0.7 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M032_0.6 RRM 5 70
M032_0.6 RRM 84 151
M032_0.6 KH 195 258
M032_0.6 KH 276 341
M032_0.6 KH 429 492
M032_0.6 KH 511 575

RNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000320204 RRM 5 70
ENSP00000320204 RRM 84 151
ENSP00000320204 KH 195 258
ENSP00000320204 KH 276 341
ENSP00000320204 KH 386 449
ENSP00000320204 KH 468 532
ENSP00000371634 RRM 5 70
ENSP00000371634 RRM 84 151
ENSP00000371634 KH 195 258
ENSP00000371634 KH 276 341
ENSP00000371634 KH 429 492
ENSP00000371634 KH 511 575
ENSP00000410242 RRM 23 96
ENSP00000410242 KH 140 202
ENSP00000413787 RRM 16 89
ENSP00000413787 KH 133 196
ENSP00000413787 KH 214 279
ENSP00000413787 KH 367 430
ENSP00000413787 KH 449 513

Links

Other KH,RRM family RBPs
Other Homo sapiens RBPs

94 Related RBPs

Due to potential differences in protein isoforms or tested constructs, some RBPs without inferred motifs might appear in this list.
Name Species Gene ID Motif Evidence RBD
Identity		 Action
Ame_R004727 Ailuropoda melanoleuca Ame_R004727 I 0.749
IGF2BP1 Anolis carolinensis ENSACAG00000006199 I 0.766
IGF2BP2 Anolis carolinensis ENSACAG00000007995 N 0.886
IGF2BP3 Anolis carolinensis ENSACAG00000013538 I 0.772
IGF2BP3 Bos taurus ENSBTAG00000019406 N 0.722
IGF2BP1 Bos taurus ENSBTAG00000011736 I 0.749
IGF2BP2 Bos taurus ENSBTAG00000007666 N 0.970
IGF2BP2 Callithrix jacchus ENSCJAG00000014731 N 0.994
IGF2BP3 Callithrix jacchus ENSCJAG00000001499 I 0.741
LOC100395821 Callithrix jacchus ENSCJAG00000007258 I 0.749
IGF2BP1 Canis familiaris ENSCAFG00000016907 I 0.746
IGF2BP2 Canis familiaris ENSCAFG00000013297 N 0.973
IGF2BP1 Cavia porcellus ENSCPOG00000020174 I 0.716
IGF2BP3 Cavia porcellus ENSCPOG00000015070 N 0.757
IGF2BP2 Cavia porcellus ENSCPOG00000005471 N 0.976
igf2bp2a Danio rerio ENSDARG00000003421 I 0.860
igf2bp3 Danio rerio ENSDARG00000010266 I 0.743
igf2bp1 Danio rerio ENSDARG00000061478 I 0.754
Igf2bp3 Dipodomys ordii ENSDORG00000014185 I 0.741
LOC100059313 Equus caballus ENSECAG00000020685 N 0.970
LOC100067926 Equus caballus ENSECAG00000016797 N 0.701
IGF2BP1 Equus caballus ENSECAG00000009723 I 0.749
IGF2BP2 Erinaceus europaeus ENSEEUG00000009674 N 0.763
IGF2BP2 Felis catus ENSFCAG00000005369 N 0.859
IF2B3_CHICK Gallus gallus ENSGALG00000010961 I 0.777
LOC424865 Gallus gallus ENSGALG00000006523 I 0.845
IF2B1_CHICK Gallus gallus ENSGALG00000001293 I 0.761
IGF2BP1 Gasterosteus aculeatus ENSGACG00000005318 I 0.744
IGF2BP2 Gasterosteus aculeatus ENSGACG00000005991 I 0.847
ENSGGOG00000024907 Gorilla gorilla ENSGGOG00000024907 I 0.916
IGF2BP2 Gorilla gorilla ENSGGOG00000015035 N 0.982
IGF2BP1 Gorilla gorilla ENSGGOG00000008872 I 0.731
IGF2BP3 Homo sapiens ENSG00000136231 D 0.741
IGF2BP1 Homo sapiens ENSG00000159217 D 0.749
IGF2BP2 Loxodonta africana ENSLAFG00000017156 N 0.973
IGF2BP3 Loxodonta africana ENSLAFG00000011924 N 0.719
IGF2BP1 Loxodonta africana ENSLAFG00000002048 I 0.749
IGF2BP2 Macaca mulatta ENSMMUG00000023416 I 0.997
IGF2BP1 Macaca mulatta ENSMMUG00000011533 I 0.744
IGF2BP3 Macaca mulatta ENSMMUG00000004839 I 0.741
IGF2BP1 Meleagris gallopavo ENSMGAG00000002497 N 0.734
IGF2BP2 Meleagris gallopavo ENSMGAG00000002904 N 0.895
IGF2BP3 Meleagris gallopavo ENSMGAG00000010497 N 0.754
IGF2BP3 Microcebus murinus ENSMICG00000013683 I 0.727
IGF2BP1 Microcebus murinus ENSMICG00000013324 I 0.746
IGF2BP1 Monodelphis domestica ENSMODG00000012268 I 0.751
IGF2BP2 Monodelphis domestica ENSMODG00000002822 N 0.853
IGF2BP3 Monodelphis domestica ENSMODG00000001014 I 0.758
Igf2bp1 Mus musculus ENSMUSG00000013415 I 0.746
Igf2bp3 Mus musculus ENSMUSG00000029814 I 0.744
Igf2bp2 Mus musculus ENSMUSG00000033581 I 0.972
IGF2BP3 Myotis lucifugus ENSMLUG00000008451 N 0.740
IGF2BP3 Ornithorhynchus anatinus ENSOANG00000014203 I 0.755
IGF2BP2 Ornithorhynchus anatinus ENSOANG00000004648 N 0.907
IGF2BP1 Oryctolagus cuniculus ENSOCUG00000004411 I 0.741
IGF2BP2 Oryctolagus cuniculus ENSOCUG00000005057 I 0.992
IGF2BP3 Oryctolagus cuniculus ENSOCUG00000008976 N 0.757
IGF2BP2 Oryzias latipes ENSORLG00000016532 I 0.817
IGF2BP3 Oryzias latipes ENSORLG00000004712 I 0.739
IGF2BP1 Otolemur garnettii ENSOGAG00000001270 I 0.711
IGF2BP1 Pan troglodytes ENSPTRG00000009368 I 0.746
XR_025001.1 Pan troglodytes ENSPTRG00000015705 I 1.000
XR_022832.1 Pan troglodytes ENSPTRG00000018986 I 0.741
ENSPPYG00000008913 Pongo pygmaeus ENSPPYG00000008913 I 0.749
ENSPPYG00000014373 Pongo pygmaeus ENSPPYG00000014373 N 0.883
IGF2BP2 Procavia capensis ENSPCAG00000015093 N 0.868
IGF2BP2 Pteropus vampyrus ENSPVAG00000011494 I 0.916
D3ZB84_RAT Rattus norvegicus ENSRNOG00000009052 I 0.746
Igf2bp2 Rattus norvegicus ENSRNOG00000025946 I 0.975
Igf2bp1 Rattus norvegicus ENSRNOG00000006122 I 0.746
IGF2BP3 Taeniopygia guttata ENSTGUG00000002773 I 0.777
IGF2BP2 Taeniopygia guttata ENSTGUG00000006719 N 0.895
IGF2BP2 Takifugu rubripes ENSTRUG00000009908 I 0.817
IGF2BP3 Takifugu rubripes ENSTRUG00000006094 I 0.736
IGF2BP3 Tetraodon nigroviridis ENSTNIG00000017755 I 0.739
IGF2BP2 Tetraodon nigroviridis ENSTNIG00000016472 I 0.800
IGF2BP1 Tetraodon nigroviridis ENSTNIG00000013986 I 0.741
IGF2BP3 Tursiops truncatus ENSTTRG00000008921 I 0.746
IGF2BP2 Tursiops truncatus ENSTTRG00000008241 N 0.880
IGF2BP1 Tursiops truncatus ENSTTRG00000007197 I 0.728
IGF2BP3 Vicugna pacos ENSVPAG00000000613 N 0.757
O57526 Xenopus laevis O57526 I 0.779
AAI70479 Xenopus laevis AAI70479 I 0.779
AAI70477 Xenopus laevis AAI70477 I 0.779
AAI70224 Xenopus laevis AAI70224 I 0.779
AAI70196 Xenopus laevis AAI70196 I 0.779
AAH57700 Xenopus laevis AAH57700 I 0.779
AAC41285 Xenopus laevis AAC41285 I 0.779
AAC18598 Xenopus laevis AAC18598 I 0.779
AAC18597 Xenopus laevis AAC18597 I 0.779
AAB97457 Xenopus laevis AAB97457 I 0.779
O73932 Xenopus laevis O73932 I 0.779
igf2bp3 Xenopus tropicalis ENSXETG00000007396 I 0.787