pum (Drosophila melanogaster)
PUF

RBP Information

Pfam ID Interpro ID Gene ID CISBP-RNA ID Sequence source
PF00806 (PUF) IPR001313 FBgn0003165 T24305_0.6 Ensembl (2011-Oct-26) Link out

Directly determined binding motifs

Name/Motif ID Species Sequence Logo IUPAC Type/Study/Study ID RBD
Identity
pum
M285_0.6		 Drosophila melanogaster Sequence logo not available HHUGUAHAUAHDHWDD RIP-chip
Cook et al.(2011)
323_16537387 		(Direct)
pum
M045_0.6		 Drosophila melanogaster UGUAHAK RNAcompete
Ray et al.(2013)
RNCMPT00046 		(Direct)
pum
M097_0.6		 Drosophila melanogaster UGUAMAK RNAcompete
Ray et al.(2013)
RNCMPT00101 		(Direct)
pum
M098_0.6		 Drosophila melanogaster UGUAYAK RNAcompete
Ray et al.(2013)
RNCMPT00102 		(Direct)
pum
M099_0.6		 Drosophila melanogaster UGUAMRK RNAcompete
Ray et al.(2013)
RNCMPT00103 		(Direct)
pum
M100_0.6		 Drosophila melanogaster UGUAMAK RNAcompete
Ray et al.(2013)
RNCMPT00104 		(Direct)
pum
M101_0.6		 Drosophila melanogaster UGUAWDU RNAcompete
Ray et al.(2013)
RNCMPT00105 		(Direct)

Motifs from related RBPs

Name/Motif ID Species Sequence Logo IUPAC Type/Study/Study ID RBD
Identity
PUM2
M249_0.6 		Homo sapiens Sequence logo not available UGUAHAUA RIP-chip
Cook et al.(2011)
1147_18776931 		0.809
PUM2
M284_0.6 		Homo sapiens Sequence logo not available GNNNNNNNNNNNUGUA yeast three-hybrid s
Cook et al.(2011)
320_15607425 		0.809
PUM2
M280_0.6 		Homo sapiens Sequence logo not available UGUANAUA PAR-clip
Cook et al.(2011)
278_20371350 		0.809
Pum2
M287_0.6 		Mus musculus UGUANAUARNNNNBBBBSCC SELEX
Cook et al.(2011)
330_11780640 		0.806
Pum2
M286_0.6 		Mus musculus UGUA SELEX
Cook et al.(2011)
329_11780640 		0.806
PUM1
M283_0.6 		Homo sapiens Sequence logo not available UGUAHAUA RIP-chip
Cook et al.(2011)
309_18776931 		0.781
PUM1
M255_0.6 		Homo sapiens Sequence logo not available UGUAHAUA RIP-chip
Cook et al.(2011)
1182_18411299 		0.781
For this family, RBPs with RBD identity > 0.7 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M045_0.6 PUF 51 85
M045_0.6 PUF 87 120
M045_0.6 PUF 123 157
M045_0.6 PUF 159 193
M045_0.6 PUF 195 229
M045_0.6 PUF 231 265
M045_0.6 PUF 267 301
M045_0.6 PUF 308 341
M097_0.6 PUF 21 55
M097_0.6 PUF 57 90
M097_0.6 PUF 93 127
M097_0.6 PUF 129 163
M097_0.6 PUF 165 199
M097_0.6 PUF 201 235
M097_0.6 PUF 237 271
M097_0.6 PUF 278 311
M098_0.6 PUF 21 55
M098_0.6 PUF 57 90
M098_0.6 PUF 93 127
M098_0.6 PUF 129 163
M098_0.6 PUF 165 199
M098_0.6 PUF 201 235
M098_0.6 PUF 237 271
M098_0.6 PUF 278 311
M099_0.6 PUF 21 55
M099_0.6 PUF 57 90
M099_0.6 PUF 93 127
M099_0.6 PUF 129 163
M099_0.6 PUF 165 199
M099_0.6 PUF 201 235
M099_0.6 PUF 237 271
M099_0.6 PUF 278 311
M100_0.6 PUF 21 55
M100_0.6 PUF 57 90
M100_0.6 PUF 93 127
M100_0.6 PUF 129 163
M100_0.6 PUF 165 199
M100_0.6 PUF 201 235
M100_0.6 PUF 237 271
M100_0.6 PUF 278 311
M101_0.6 PUF 21 55
M101_0.6 PUF 57 90
M101_0.6 PUF 93 127
M101_0.6 PUF 129 163
M101_0.6 PUF 165 199
M101_0.6 PUF 201 235
M101_0.6 PUF 237 271
M101_0.6 PUF 278 311

RNA Binding Domains

Protein ID Domain From To Sequence
FBpp0081470 PUF 1111 1145
FBpp0081470 PUF 1147 1180
FBpp0081470 PUF 1183 1217
FBpp0081470 PUF 1219 1253
FBpp0081470 PUF 1255 1289
FBpp0081470 PUF 1291 1325
FBpp0081470 PUF 1327 1361
FBpp0081470 PUF 1368 1401
FBpp0081471 PUF 1111 1145
FBpp0081471 PUF 1147 1180
FBpp0081471 PUF 1183 1217
FBpp0081471 PUF 1219 1253
FBpp0081471 PUF 1255 1289
FBpp0081471 PUF 1291 1325
FBpp0081471 PUF 1327 1361
FBpp0081471 PUF 1368 1401
FBpp0081472 PUF 1111 1145
FBpp0081472 PUF 1147 1180
FBpp0081472 PUF 1183 1217
FBpp0081472 PUF 1219 1253
FBpp0081472 PUF 1255 1289
FBpp0081472 PUF 1291 1325
FBpp0081472 PUF 1327 1361
FBpp0081472 PUF 1368 1401
FBpp0081473 PUF 763 797
FBpp0081473 PUF 799 832
FBpp0081473 PUF 835 869
FBpp0081473 PUF 871 905
FBpp0081473 PUF 907 941
FBpp0081473 PUF 943 977
FBpp0081473 PUF 979 1013
FBpp0081473 PUF 1020 1053
FBpp0081474 PUF 513 547
FBpp0081474 PUF 549 582
FBpp0081474 PUF 585 619
FBpp0081474 PUF 621 655
FBpp0081474 PUF 657 691
FBpp0081474 PUF 693 727
FBpp0081474 PUF 729 763
FBpp0081474 PUF 770 803
FBpp0293727 PUF 503 537
FBpp0293727 PUF 539 572
FBpp0293727 PUF 575 609
FBpp0293727 PUF 611 645
FBpp0293727 PUF 647 681
FBpp0293727 PUF 683 717
FBpp0293727 PUF 719 753
FBpp0293727 PUF 760 793

Links

Other PUF family RBPs
Other Drosophila melanogaster RBPs

90 Related RBPs

Due to potential differences in protein isoforms or tested constructs, some RBPs without inferred motifs might appear in this list.
Name Species Gene ID Motif Evidence RBD
Identity		 Action
GM26283 Drosophila sechellia FBgn0181138 I 1.000
GE24797 Drosophila yakuba FBgn0241899 I 0.996
GG17394 Drosophila erecta FBgn0109620 I 0.996
GK14049 Drosophila willistoni FBgn0216055 I 0.993
GF18428 Drosophila ananassae FBgn0095446 I 0.993
GA27465-RA Drosophila pseudoobscura FBgn0248832 I 0.989
GJ10105 Drosophila virilis FBgn0197393 I 0.982
GH15257 Drosophila grimshawi FBgn0122732 I 0.978
GL22345 Drosophila persimilis FBgn0159937 I 0.978
GI22503 Drosophila mojavensis FBgn0145231 I 0.975
CPIJ016844 Culex quinquefasciatus CPIJ016844 I 0.896
CpipJ_CPIJ016844 Culex pipiens CpipJ_CPIJ016844 I 0.896
AGAP003914 Anopheles gambiae AGAP003914 I 0.888
AAEL012420 Aedes aegypti AAEL012420 I 0.885
DGIL_AUG5s1082g1t1 Acyrtosiphon pisum DGIL_AUG5s1082g1t1 I 0.881
amel4_ncbi_hmm4895 Apis mellifera amel4_ncbi_hmm4895 I 0.878
nasonia_NCBI_hmm823294 Nasonia vitripennis nasonia_NCBI_hmm823294 I 0.867
BGIBMGA003401 Bombyx mori BGIBMGA003401 I 0.867
PHUM490070 Pediculus humanus PHUM490070 I 0.845
XP_001187223.1 Strongylocentrotus purpuratus XP_001187223.1 I 0.824
XP_794621.2 Strongylocentrotus purpuratus XP_794621.2 I 0.824
PASA_GEN_0800110 Daphnia pulex PASA_GEN_0800110 I 0.824
ENSOANG00000003230 Ornithorhynchus anatinus ENSOANG00000003230 I 0.820
Q2VB18_CHICK Gallus gallus ENSGALG00000016481 I 0.820
PUM2 Taeniopygia guttata ENSTGUG00000013149 I 0.820
PUM2 Oryctolagus cuniculus ENSOCUG00000017908 I 0.817
PUM2 Equus caballus ENSECAG00000021930 I 0.817
ENSPPYG00000012617 Pongo pygmaeus ENSPPYG00000012617 I 0.817
PUM2 Meleagris gallopavo ENSMGAG00000014040 I 0.817
PUM2 Bos taurus ENSBTAG00000011155 I 0.817
PUM2 Callithrix jacchus ENSCJAG00000007450 I 0.817
PUM2 Sus scrofa ENSSSCG00000008600 I 0.817
PUM2 Cavia porcellus ENSCPOG00000007075 I 0.817
PUM2 Homo sapiens ENSG00000055917 D 0.817
Pum2 Mus musculus ENSMUSG00000020594 D 0.813
PUM2 Anolis carolinensis ENSACAG00000010491 I 0.813
PUM2 Monodelphis domestica ENSMODG00000009811 I 0.809
PUM2 Vicugna pacos ENSVPAG00000005056 I 0.809
Ame_R002800 Ailuropoda melanoleuca Ame_R002800 I 0.809
Pum2 Rattus norvegicus ENSRNOG00000006180 I 0.809
PUM2 Gorilla gorilla ENSGGOG00000011374 I 0.809
PUM2 Canis familiaris ENSCAFG00000003839 I 0.809
PUM2 Pan troglodytes ENSPTRG00000011692 I 0.809
PUM2 Loxodonta africana ENSLAFG00000009278 I 0.806
PUM2 Tupaia belangeri ENSTBEG00000008729 I 0.806
PUM2 Takifugu rubripes ENSTRUG00000018167 I 0.799
PUM1 Monodelphis domestica ENSMODG00000017067 I 0.795
PUM2 Oryzias latipes ENSORLG00000012611 I 0.795
PUM1 Anolis carolinensis ENSACAG00000000682 I 0.795
estExt_Genewise1Plus.C_sca_670070 Lottia gigantea estExt_Genewise1Plus.C_sca_670070 I 0.795
estExt_Genewise1Plus.C_4390035 Capitella teleta estExt_Genewise1Plus.C_4390035 I 0.792
PUM1 Meleagris gallopavo ENSMGAG00000000724 I 0.791
PUM2 Tursiops truncatus ENSTTRG00000004887 I 0.791
pum2 Xenopus tropicalis ENSXETG00000008903 I 0.791
PUM1_CHICK Gallus gallus ENSGALG00000000597 I 0.791
AAH80379 Xenopus laevis AAH80379 I 0.788
PUM1 Oryzias latipes ENSORLG00000011482 I 0.788
e_gw.54.41.1 Nematostella vectensis e_gw.54.41.1 I 0.788
BAB20864 Xenopus laevis BAB20864 I 0.788
BAC57980 Xenopus laevis BAC57980 I 0.788
PUM2 Tarsius syrichta ENSTSYG00000014463 I 0.788
PUM2 Gasterosteus aculeatus ENSGACG00000009670 I 0.788
Pum1 Rattus norvegicus ENSRNOG00000011709 I 0.784
PUM1 Microcebus murinus ENSMICG00000007713 I 0.784
Pum1 Mus musculus ENSMUSG00000028580 I 0.784
AAL14121 Xenopus laevis AAL14121 I 0.784
PUM1 Sorex araneus ENSSARG00000003055 I 0.781
ENSPPYG00000001621 Pongo pygmaeus ENSPPYG00000001621 I 0.781
PUM1 Bos taurus ENSBTAG00000018979 I 0.781
PUM1 Erinaceus europaeus ENSEEUG00000003871 I 0.781
PUM1 Oryctolagus cuniculus ENSOCUG00000008641 I 0.781
PUM1 Homo sapiens ENSG00000134644 D 0.781
Q3YAQ1_MACMU Macaca mulatta ENSMMUG00000013520 I 0.781
PUM1 Vicugna pacos ENSVPAG00000005902 I 0.777
PUM1 Equus caballus ENSECAG00000021369 I 0.777
Ame_R012380 Ailuropoda melanoleuca Ame_R012380 I 0.777
PUM1 Canis familiaris ENSCAFG00000011205 I 0.777
PUM1 Loxodonta africana ENSLAFG00000003178 I 0.777
PUM1 Pan troglodytes ENSPTRG00000000453 I 0.777
LOC100415491 Callithrix jacchus ENSCJAG00000006035 I 0.777
e_gw1.9.429.1 Trichoplax adhaerens e_gw1.9.429.1 I 0.774
PUM1 Takifugu rubripes ENSTRUG00000013121 I 0.773
PUM1 Sus scrofa ENSSSCG00000003591 I 0.773
PUM1 Gasterosteus aculeatus ENSGACG00000005717 I 0.770
PUM1 Pteropus vampyrus ENSPVAG00000005207 I 0.770
PUM1 Tursiops truncatus ENSTTRG00000007436 I 0.770
PUM1 Tetraodon nigroviridis ENSTNIG00000016983 I 0.755
ENSCING00000003888 Ciona intestinalis ENSCING00000003888 I 0.716
105390 Helobdella robusta 105390 I 0.712